SCHEMBL3381295

SCHEMBL3381295

N=C(N)NCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CTSL P07711 3/20 0.64
PTGER4 P35408 1/20 0.55
CTSB P07858 1/20 0.54
CTSS P25774 1/20 0.54
CTSK P43235 1/20 0.54
TACR1 P25103 2/20 0.53
FOLH1 Q04609 1/20 0.53
SIRT2 Q8IXJ6 1/20 0.52
SIRT1 Q96EB6 1/20 0.52
ITGB3 P05106 1/20 0.52
ITGAV P06756 1/20 0.52
ECE1 P42892 1/20 0.52
GNPAT O15228 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11411256 0.95 CTSL (0.56) CTSLPTGER4CTSSFOLH1SIRT2
SCHEMBL5929274 0.94 CTSL (0.73) CTSLCTSBCTSSCTSKTACR1
SCHEMBL10787733 0.94 NPY4R (0.61) CTSLCTSB
SCHEMBL10787739 0.94 NPY4R (0.61) CTSLCTSB
SCHEMBL29473451 0.93 CTSL (0.59) CTSLPTGER4CTSBCTSSCTSK
SCHEMBL8595664 0.93 CTSL (0.56) CTSLPTGER4CTSBCTSSCTSK
SCHEMBL6768020 0.93 FOLH1 (0.59) CTSLCTSSFOLH1SIRT2SIRT1
SCHEMBL5145708 0.93 FOLH1 (0.59) CTSLCTSSFOLH1SIRT2SIRT1
SCHEMBL631840 0.93 FOLH1 (0.59) CTSLCTSSFOLH1SIRT2SIRT1
SCHEMBL19784348 0.92 CTSL (0.66) CTSLPTGER4CTSBCTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220177947-A1 Compounds to Identify Beta-Lactamases, and Methods of Use Thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-06-09 US claimed
EP-1833982-B1 HEMOSTASIS ASSAY STICHTING KATHOLIEKE UNIV (NL) 2010-12-01 EP claimed
US-20250263393-A1 FAP INHIBITORS SHANGHAI SINOTAU BIOTECH. CO., LTD (CN) 2025-08-21 US disclosed
EP-4590664-A1 INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN AND USE THEREOF Shanghai Sinotau Biotech. Co., Ltd (CN) 2025-07-30 EP disclosed
CN-120202191-A Inhibitors of prostate specific membrane antigen and uses thereof 上海先通生物科技有限公司 2025-06-24 CN disclosed
WO-2025055943-A1 INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN AND USE THEREOF SHANGHAI SINOTAU BIOTECH. CO., LTD (CN) 2025-03-20 WO disclosed
WO-2025055942-A1 INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN AND USE THEREOF SHANGHAI SINOTAU BIOTECH. CO., LTD (CN) 2025-03-20 WO disclosed
EP-4511367-A1 FAP INHIBITORS Shanghai Sinotau Biotech. Co., Ltd (CN) 2025-02-26 EP disclosed
CN-119072472-A FAP inhibitors 上海先通生物科技有限公司 2024-12-03 CN disclosed
US-20240279586-A1 Biological Indicator with Adjusted Resistance Characteristics SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2024-08-22 US disclosed
EP-3585447-B1 PROCESS FOR THE PREPARATION OF DOUBLE CROSSLINKED CORE-SHELL POLYMERIC NANOPARTICLES FOR MULTIMODAL IMAGING AND THERANOSTIC APPLICATIONS FONDAZIONE ST ITALIANO TECNOLOGIA (IT) 2024-07-24 EP disclosed
US-20220257604-A1 COMPOSITIONS AND METHODS FOR MODULATING VIRAL INFECTIONS BY REGULATING GLUCOSYLCERAMIDES UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2022-08-18 US disclosed
CN-114728008-A Compounds for identifying beta-lactamases and methods of use thereof 加利福尼亚大学董事会 2022-07-08 CN disclosed
US-11311853-B2 Process for the preparation of double crosslinked core-shell polymeric nanoparticles for multimodal imaging and theranostic applications FONDAZIONE ISTITUTO ITALIANO Dl TECNOLOGIA (IT) 2022-04-26 US disclosed
WO-2022034498-A1 MOVING-FRONT STERILIZATION MONITORING DEVICES 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-02-17 WO disclosed
US-10421725-B2 Alkoxyamines for the treatment of cancers CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2019-09-24 US disclosed
US-20160115130-A1 ALKOXYAMINES FOR THE TREATMENT OF CANCERS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2016-04-28 US disclosed
EP-3010881-A1 ALKOXYAMINES FOR THE TREATMENT OF CANCERS Centre National de la Recherche Scientifique (FR) 2016-04-27 EP disclosed
WO-2015001436-A1 ALKOXYAMINES FOR THE TREATMENT OF CANCERS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2015-01-08 WO disclosed
EP-2816027-A1 Alkoxyamines for the treatment of cancers Centre National De La Recherche Scientifique (FR) 2014-12-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220177947-A1 Compounds to Identify Beta-Lactamases, and Methods of Use Thereof GUSB, GLB1, MGAM CTSL 85/4885PTGER4 3965/4885CTSB 168/4885
US-20160115130-A1 ALKOXYAMINES FOR THE TREATMENT OF CANCERS ERBB2, ALK, EGFR CTSL 3927/4885PTGER4 1742/4885CTSB 1993/4885
US-20250263393-A1 FAP INHIBITORS FAP, APC, FIBP CTSL 154/4885PTGER4 3614/4885CTSB 86/4885
US-10421725-B2 Alkoxyamines for the treatment of cancers ERBB2, ALK, EGFR CTSL 3927/4885PTGER4 1742/4885CTSB 1993/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.