SCHEMBL26433360

SCHEMBL26433360

c1ccc(-c2cc3c(cn2)c2cnc(-c4ccccn4)c4c5cc6c7c(-c8ccccn8)ncc8c9cnc(-c%10ccccn%10)cc9n(c6cc5n3c24)c87)nc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 4/20 0.43
KDM4E B2RXH2 5/20 0.36
NPC1 O15118 2/20 0.36
METAP1 P53582 4/20 0.36
LMNA P02545 3/20 0.36
CCR1 P32246 3/20 0.36
CCR5 P51681 3/20 0.36
CCR8 P51685 3/20 0.36
METAP2 P50579 1/20 0.36
CYP1A2 P05177 1/20 0.36
POLB P06746 1/20 0.36
BLM P54132 1/20 0.36
HIF1A Q16665 1/20 0.36
DOHH Q9BU89 1/20 0.36
P4HTM Q9NXG6 1/20 0.36
ADORA3 P0DMS8 1/20 0.33
MCL1 Q07820 3/20 0.33
PIM2 Q9P1W9 2/20 0.33
PIM3 Q86V86 1/20 0.33
TP53 P04637 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26433334 0.79 IDO1 (0.38) PIM1NPC1PIM2PIM3RAB9A
SCHEMBL26433362 0.75 PIM1 (0.46) PIM1CYP1A2PIM2PIM3ALOX15
SCHEMBL26433276 0.72 PIM1 (0.40) PIM1KDM4ENPC1METAP1LMNA
SCHEMBL26433357 0.70 TDO2 (0.41) KDM4ENPC1LMNAHTTSMN1; SMN2
SCHEMBL163378 0.60 KDM4E (0.78) PIM1KDM4ENPC1METAP1LMNA
Dipyridyl SCHEMBL29351528 0.60 KDM4E (1.00) KDM4ENPC1METAP1LMNACCR1
Dipyridyl SCHEMBL5922 0.60 KDM4E (1.00) KDM4ENPC1METAP1LMNACCR1
Dipyridyl SCHEMBL3711450 0.60 KDM4E (1.00) KDM4ENPC1METAP1LMNACCR1
Dipyridyl SCHEMBL29907716 0.60 KDM4E (1.00) KDM4ENPC1METAP1LMNACCR1
Dipyridyl SCHEMBL2383343 0.58 KDM4E (0.93) KDM4ENPC1METAP1LMNACCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230126543-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-04-27 US disclosed
US-20230126543-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230126543-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE CYP1A1, AOX1, CRY1 PIM1 1525/4885KDM4E 2983/4885NPC1 2471/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.