Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 6/20 | 0.49 |
| ▸ | GIPR | P48546 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 7/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | VIPR2 | P41587 | 1/20 | 0.42 |
| ▸ | GLP1R | P43220 | 1/20 | 0.42 |
| ▸ | SUV39H1 | O43463 | 1/20 | 0.41 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4617619 | 0.82 | GCGR (0.68) | GCGRGIPRVIPR2GLP1R | |
| SCHEMBL2643224 | 0.82 | GCGR (0.68) | GCGRGIPRVIPR2GLP1R | |
| SCHEMBL23927784 | 0.82 | GCGR (0.74) | GCGRGIPRVIPR2GLP1R | |
| SCHEMBL2642906 | 0.76 | GCGR (0.61) | GCGRGIPRVIPR2GLP1R | |
| SCHEMBL2643243 | 0.75 | GCGR (0.67) | GCGRGIPRVIPR2GLP1R | |
| SCHEMBL2657857 | 0.74 | GCGR (0.80) | GCGRGIPRVIPR2GLP1R | |
| SCHEMBL2644894 | 0.74 | GCGR (0.80) | GCGRGIPRVIPR2GLP1R | |
| SCHEMBL2643194 | 0.72 | GCGR (0.66) | GCGRGIPRVIPR2GLP1R | |
| SCHEMBL2643139 | 0.70 | GCGR (0.53) | GCGRGIPRTP53MDM2VIPR2 | |
| SCHEMBL13619468 | 0.70 | GCGR (0.59) | GCGRGIPRVIPR2GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070088070-A1 | Pyrazole derivatives, compositions containing such compounds and methods of use | PARMEE EMMA R | 2007-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070088070-A1 | Pyrazole derivatives, compositions containing such compounds and methods of use | PC, GOT2, PNLIP | GCGR 188/4885GIPR 205/4885TP53 1937/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.