SCHEMBL26434306

SCHEMBL26434306

OC(O)c1cccc2c1Cc1ccccc1-2

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.49
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
HTR7 P34969 2/20 0.43
HTR2B P41595 2/20 0.43
SRD5A2 P31213 1/20 0.40
MAOA P21397 1/20 0.38
DRD2 P14416 2/20 0.37
ADRA1D P25100 1/20 0.37
HTR2A P28223 1/20 0.37
HTR2C P28335 1/20 0.37
ADRA1A P35348 1/20 0.37
ADRA1B P35368 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA4 P22748 1/20 0.37
CA6 P23280 1/20 0.37
ALDH1A1 P00352 3/20 0.36
KDM4E B2RXH2 1/20 0.36
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2231457 0.85 NPC1 (0.47) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL29067758 0.82 PNMT (0.44) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL11760362 0.81 PNMT (0.42) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL28846461 0.81 PNMT (0.42) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL7606251 0.81 PNMT (0.49) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL29617348 0.81 PNMT (0.49) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL10516045 0.81 PNMT (0.49) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL6672847 0.81 PNMT (0.49) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL6675580 0.81 PNMT (0.49) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL7056973 0.80 PNMT (0.45) PNMTNPC1RAB9AHTR7HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230331689-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LT MATERIALS CO., LTD. (KR) 2023-10-19 US disclosed
US-20230131749-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LT MATERIALS CO., LTD. (KR) 2023-04-27 US disclosed
US-20230131749-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LT MATERIALS CO., LTD. (KR) 2023-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230131749-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME CRY1, CYP1A1, CYP1B1 PNMT 1500/4885NPC1 2682/4885RAB9A 2261/4885
US-20230331689-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME CRY1, CRY2, CYP1A1 PNMT 1710/4885NPC1 2499/4885RAB9A 2513/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.