Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | IL1B | P01584 | 3/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.33 |
| ▸ | LATS1 | O95835 | 1/20 | 0.33 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26435052 | 0.91 | NLRP3 (0.47) | NLRP3KCNH2IL1BTNFKDM4E | |
| SCHEMBL26436140 | 0.88 | NLRP3 (0.62) | NLRP3KCNH2IL1BTNF | |
| SCHEMBL26436151 | 0.87 | NLRP3 (0.44) | NLRP3KCNH2IL1BTNFHTR1A | |
| SCHEMBL26435322 | 0.87 | NLRP3 (0.44) | NLRP3KCNH2IL1BTNFHTT | |
| SCHEMBL26435077 | 0.85 | NLRP3 (0.57) | NLRP3KCNH2IL1BTNFKDM4E | |
| SCHEMBL26434879 | 0.81 | NLRP3 (0.46) | NLRP3IL1BTNFKDM4EHSD17B10 | |
| SCHEMBL29131981 | 0.78 | IL1B (0.52) | NLRP3IL1BKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL29131979 | 0.78 | IL1B (0.52) | NLRP3IL1BKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL30624974 | 0.78 | IL1B (0.52) | NLRP3IL1BKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL26436166 | 0.78 | NLRP3 (0.43) | NLRP3KCNH2IL1BTNFKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066377-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 索智生物科技（浙江）有限公司 | 2023-04-27 | — | — | WO | disclosed |