Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | IL1B | P01584 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 3/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26435053 | 0.90 | NLRP3 (0.41) | NLRP3KDM4EHSD17B10GAAMAPT | |
| SCHEMBL26436141 | 0.87 | IL1B (0.52) | IL1BTNF | |
| SCHEMBL26435325 | 0.86 | NLRP3 (0.37) | NLRP3KDM4EGAAMAPTIL1B | |
| SCHEMBL26436155 | 0.86 | NLRP3 (0.39) | NLRP3KDM4EGAAMAPTIL1B | |
| SCHEMBL26434881 | 0.84 | IL1B (0.49) | NLRP3KDM4EHSD17B10GAAMAPT | |
| SCHEMBL26435079 | 0.84 | NLRP3 (0.50) | NLRP3KDM4EHSD17B10GAAMAPT | |
| SCHEMBL26434878 | 0.81 | NLRP3 (0.48) | NLRP3KDM4EHSD17B10GAAMAPT | |
| SCHEMBL29131981 | 0.81 | IL1B (0.52) | NLRP3KDM4EHSD17B10GAAIL1B | |
| SCHEMBL29131979 | 0.81 | IL1B (0.52) | NLRP3KDM4EHSD17B10GAAIL1B | |
| SCHEMBL30624974 | 0.81 | IL1B (0.52) | NLRP3KDM4EHSD17B10GAAIL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066377-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 索智生物科技（浙江）有限公司 | 2023-04-27 | — | — | WO | disclosed |