Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.34 |
| ▸ | MEN1 | O00255 | 6/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | IL1B | P01584 | 6/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26435325 | 0.92 | NLRP3 (0.37) | NLRP3HTTSLC6A2KMT2AMEN1 | |
| SCHEMBL26436167 | 0.91 | NLRP3 (0.35) | NLRP3HTTSLC6A2KMT2AMEN1 | |
| SCHEMBL26434879 | 0.86 | NLRP3 (0.46) | NLRP3HTTKMT2AMAPTKDM4E | |
| SCHEMBL26436156 | 0.86 | IL1B (0.48) | NLRP3HTTSLC6A2KMT2AMEN1 | |
| SCHEMBL26436031 | 0.85 | NLRP3 (0.44) | NLRP3HTTSLC6A2KMT2AMEN1 | |
| SCHEMBL26436151 | 0.83 | NLRP3 (0.44) | NLRP3IL1BTNFKAT2B | |
| SCHEMBL26435664 | 0.83 | IL1B (0.34) | NLRP3HTTSLC6A2KMT2AMEN1 | |
| SCHEMBL26436149 | 0.82 | NLRP3 (0.62) | NLRP3IL1BKAT2B | |
| SCHEMBL26435636 | 0.81 | IL1B (0.48) | IL1BTNF | |
| SCHEMBL26435359 | 0.79 | NLRP3 (0.44) | NLRP3HTTSLC6A2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066377-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 索智生物科技（浙江）有限公司 | 2023-04-27 | — | — | WO | disclosed |