SCHEMBL26435202

SCHEMBL26435202

c1ccc2c(c1)ccc1cccc(-c3nc(-c4ccc5c(c4)oc4ccccc45)nc(-c4ccc5c(c4)sc4ccccc45)n3)c12

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.35
PRKDC P78527 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ABCG2 Q9UNQ0 3/20 0.33
DUSP3 P51452 1/20 0.33
ALDH1A1 P00352 3/20 0.33
MAPT P10636 2/20 0.33
HPGD P15428 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
AHR P35869 2/20 0.33
RAB9A P51151 1/20 0.33
ALOX5 P09917 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
KDM4E B2RXH2 1/20 0.32
POLB P06746 1/20 0.32
HCRTR1 O43613 1/20 0.32
HTR2B P41595 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26435347 0.97 PRKDC (0.34) L3MBTL1PRKDCTDP1ABCG2DUSP3
SCHEMBL26047900 0.96 PRKDC (0.34) L3MBTL1PRKDCTDP1DUSP3ALDH1A1
SCHEMBL26435381 0.95 PRKDC (0.35) L3MBTL1PRKDCTDP1ABCG2DUSP3
SCHEMBL26435203 0.94 L3MBTL1 (0.35) L3MBTL1PRKDCTDP1ABCG2DUSP3
SCHEMBL26434981 0.93 ALOX5 (0.40) L3MBTL1PRKDCTDP1ABCG2ALDH1A1
SCHEMBL26435348 0.92 ABCG2 (0.33) L3MBTL1TDP1ABCG2ALDH1A1MAPT
SCHEMBL26435393 0.92 PRKDC (0.33) L3MBTL1PRKDCTDP1ABCG2DUSP3
SCHEMBL26435698 0.92 TDP1 (0.36) L3MBTL1PRKDCTDP1ABCG2ALDH1A1
SCHEMBL26435351 0.92 TDP1 (0.36) L3MBTL1PRKDCTDP1ABCG2ALDH1A1
SCHEMBL26047771 0.91 PRKDC (0.36) L3MBTL1PRKDCDUSP3ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230320205-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-10-05 US disclosed
US-20230320205-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230320205-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS NOM1, MNS1, NOS1 L3MBTL1 1536/4885PRKDC 3142/4885TDP1 1017/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.