SCHEMBL26435393

SCHEMBL26435393

c1ccc2c(c1)ccc1cccc(-c3nc(-c4ccc(-c5ccc6c(c5)oc5ccccc56)cc4)nc(-c4ccc5sc6ccccc6c5c4)n3)c12

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
HCRTR1 O43613 1/20 0.32
ABCG2 Q9UNQ0 2/20 0.31
MMP12 P39900 1/20 0.31
MMP13 P45452 1/20 0.31
DUSP3 P51452 1/20 0.31
AHR P35869 1/20 0.30
PIM3 Q86V86 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
POLB P06746 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
ALOX5 P09917 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26435381 0.97 PRKDC (0.35) PRKDCL3MBTL1TDP1HCRTR1ABCG2
SCHEMBL26435347 0.95 PRKDC (0.34) PRKDCL3MBTL1TDP1HCRTR1ABCG2
SCHEMBL26435348 0.92 ABCG2 (0.33) L3MBTL1TDP1ABCG2AHRMEN1
SCHEMBL26435202 0.92 L3MBTL1 (0.35) PRKDCL3MBTL1TDP1HCRTR1ABCG2
SCHEMBL26435028 0.91 ALOX5 (0.38) PRKDCL3MBTL1TDP1ALOX5
SCHEMBL26435395 0.90 TDP1 (0.34) L3MBTL1TDP1ABCG2AHRALDH1A1
SCHEMBL26435203 0.90 L3MBTL1 (0.35) PRKDCL3MBTL1TDP1HCRTR1ABCG2
SCHEMBL26435396 0.90 ALDH1A1 (0.34) L3MBTL1TDP1PIM3ALDH1A1POLB
SCHEMBL26435357 0.90 ALDH1A1 (0.34) L3MBTL1TDP1PIM3ALDH1A1POLB
SCHEMBL26435527 0.89 KMT2A (0.33) L3MBTL1TDP1ABCG2AHRPIM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230320205-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-10-05 US disclosed
US-20230320205-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230320205-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS NOM1, MNS1, NOS1 PRKDC 3142/4885L3MBTL1 1536/4885TDP1 1017/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.