Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 6/20 | 0.34 |
| ▸ | TNF | P01375 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 5/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 6/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26436167 | 0.92 | NLRP3 (0.35) | IL1BTNFHTTSLC6A2KAT2B | |
| SCHEMBL26435325 | 0.91 | NLRP3 (0.37) | IL1BTNFHTTSLC6A2KAT2B | |
| SCHEMBL26435636 | 0.87 | IL1B (0.48) | IL1BTNF | |
| SCHEMBL26435053 | 0.86 | NLRP3 (0.41) | IL1BTNFHTTNLRP3MAPT | |
| SCHEMBL26435667 | 0.86 | IL1B (0.48) | IL1BTNFHTTSLC6A2KAT2B | |
| SCHEMBL26435872 | 0.85 | IL1B (0.39) | IL1BHTTSLC6A2KAT2BNLRP3 | |
| SCHEMBL26437126 | 0.84 | NLRP3 (0.39) | IL1BTNFHTTSLC6A2KAT2B | |
| SCHEMBL26435657 | 0.83 | NLRP3 (0.43) | IL1BTNFHTTSLC6A2KAT2B | |
| SCHEMBL26436155 | 0.83 | NLRP3 (0.39) | IL1BTNFHTTSLC6A2KAT2B | |
| SCHEMBL26438744 | 0.82 | IL1B (0.56) | IL1BNLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066377-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 索智生物科技（浙江）有限公司 | 2023-04-27 | — | — | WO | disclosed |