Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 10/20 | 0.48 |
| ▸ | TNF | P01375 | 3/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SMO | Q99835 | 1/20 | 0.31 |
| ▸ | FLT1 | P17948 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26436168 | 0.92 | IL1B (0.48) | IL1BTNFNLRP3SLC6A2HTT | |
| SCHEMBL26435326 | 0.91 | IL1B (0.46) | IL1BTNFNLRP3SLC6A2HTT | |
| SCHEMBL26435640 | 0.88 | IL1B (0.61) | IL1BTNFNLRP3 | |
| SCHEMBL26435055 | 0.87 | IL1B (0.53) | IL1BTNFNLRP3HTTKDM4E | |
| SCHEMBL26435671 | 0.87 | IL1B (0.41) | IL1BTNFNLRP3 | |
| SCHEMBL26435664 | 0.86 | IL1B (0.34) | IL1BTNFNLRP3SLC6A2HTT | |
| SCHEMBL26435876 | 0.86 | IL1B (0.58) | IL1BTNFNLRP3KAT2BKDM4E | |
| SCHEMBL26437127 | 0.85 | IL1B (0.45) | IL1BTNFNLRP3SLC6A2HTT | |
| SCHEMBL26436156 | 0.83 | IL1B (0.48) | IL1BTNFNLRP3SLC6A2HTT | |
| SCHEMBL24855380 | 0.81 | NLRP3 (0.40) | IL1BTNFNLRP3KAT2BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066377-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 索智生物科技（浙江）有限公司 | 2023-04-27 | — | — | WO | disclosed |