Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | STAT3 | P40763 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18912355 | 0.82 | ALDH1A1 (0.40) | HRH3 | |
| SCHEMBL17194445 | 0.80 | TSHR (0.39) | — | |
| SCHEMBL22699692 | 0.80 | CYP2D6 (0.35) | JAK2ABL1KDRSTAT3GSK3B | |
| SCHEMBL13415885 | 0.77 | SIGMAR1 (0.37) | JAK2ABL1KDRSTAT3GSK3B | |
| SCHEMBL13397311 | 0.76 | JAK2 (0.32) | JAK2ABL1KDRSTAT3GSK3B | |
| SCHEMBL25800783 | 0.74 | DRD2 (0.33) | JAK2ABL1KDRSTAT3GSK3B | |
| SCHEMBL26441178 | 0.74 | SLC6A9 (0.33) | JAK2ABL1KDRSTAT3GSK3B | |
| SCHEMBL12568602 | 0.74 | SIGMAR1 (0.39) | — | |
| SCHEMBL81698 | 0.74 | SIGMAR1 (0.39) | — | |
| SCHEMBL18912360 | 0.74 | SIGMAR1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066204-A1 | SIK INHIBITOR, COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海美悦生物科技发展有限公司 | 2023-04-27 | — | — | WO | disclosed |