Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 6/20 | 0.59 |
| ▸ | CCNK | O75909 | 2/20 | 0.40 |
| ▸ | CDK7 | P50613 | 2/20 | 0.40 |
| ▸ | CCNH | P51946 | 2/20 | 0.40 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.40 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | IL1B | P01584 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26437134 | 0.90 | NLRP3 (0.48) | NLRP3CCNKCDK7CCNHMNAT1 | |
| SCHEMBL26435316 | 0.89 | NLRP3 (0.49) | NLRP3CCNKCDK7CCNHMNAT1 | |
| SCHEMBL26436532 | 0.88 | NLRP3 (0.58) | NLRP3IL1B | |
| SCHEMBL26437586 | 0.88 | NLRP3 (0.45) | NLRP3CCNKCDK7CCNHMNAT1 | |
| SCHEMBL26435070 | 0.86 | NLRP3 (0.49) | NLRP3IL1BALDH1A1 | |
| SCHEMBL29275831 | 0.85 | NLRP3 (0.81) | NLRP3CCNKCDK12CCNT1CDK9 | |
| SCHEMBL30214821 | 0.85 | NLRP3 (0.81) | NLRP3CCNKCDK12CCNT1CDK9 | |
| SCHEMBL29276147 | 0.85 | NLRP3 (0.81) | NLRP3CCNKCDK12CCNT1CDK9 | |
| SCHEMBL26437264 | 0.83 | NLRP3 (0.40) | NLRP3CCNKCDK7CCNHMNAT1 | |
| SCHEMBL26437413 | 0.82 | IL1B (0.55) | NLRP3IL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066377-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 索智生物科技（浙江）有限公司 | 2023-04-27 | — | — | WO | disclosed |