SCHEMBL26437264 — predicted protein targets

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	NLRP3	Q96P20	10/20	0.40

▸	IL1B	P01584	4/20	0.40

▸	CCNK	O75909	4/20	0.38

▸	CDK7	P50613	4/20	0.38

▸	CCNH	P51946	4/20	0.38

▸	MNAT1	P51948	4/20	0.38

▸	CDK12	Q9NYV4	4/20	0.38

▸	CCNT1	O60563	1/20	0.38

▸	CDK9	P50750	1/20	0.38

▸	KAT2B	Q92831	1/20	0.34

▸	CCNA2	P20248	2/20	0.33

▸	CDK2	P24941	2/20	0.33

▸	ROCK2	O75116	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL26437293	0.91	NLRP3 (0.49)	NLRP3IL1BCCNKCDK7CCNH
SCHEMBL26437247	0.88	IL1B (0.45)	NLRP3IL1B
SCHEMBL30374858	0.88	IL1B (0.45)	NLRP3IL1B
SCHEMBL26092496	0.88	IL1B (0.45)	NLRP3IL1B
SCHEMBL26434685	0.88	IL1B (0.52)	NLRP3IL1B
SCHEMBL26437586	0.86	NLRP3 (0.45)	NLRP3IL1BCCNKCDK7CCNH
SCHEMBL26437413	0.85	IL1B (0.55)	NLRP3IL1B
SCHEMBL26437249	0.84	NLRP3 (0.55)	NLRP3IL1BCCNKCDK12CCNT1
SCHEMBL26437152	0.83	NLRP3 (0.59)	NLRP3IL1BCCNKCDK7CCNH
SCHEMBL26434687	0.81	NLRP3 (0.49)	NLRP3IL1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023066377-A1	NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF	索智生物科技（浙江）有限公司	2023-04-27	—	—	WO	disclosed