Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM2 | O94759 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24165329 | 0.84 | LMNA (0.50) | POLBTSHRLMNATDP1NPSR1 | |
| SCHEMBL19890880 | 0.84 | LMNA (0.50) | POLBTSHRLMNATDP1NPSR1 | |
| SCHEMBL24088583 | 0.84 | LMNA (0.50) | POLBTSHRLMNATDP1NPSR1 | |
| SCHEMBL20079129 | 0.80 | TSHR (0.32) | TSHRLMNATDP1NPSR1GAA | |
| SCHEMBL23793795 | 0.80 | TSHR (0.32) | TSHRLMNATDP1NPSR1GAA | |
| SCHEMBL15708270 | 0.80 | TRPM2 (0.43) | TRPM2POLBCYP2C19CYP2C9MAPK1 | |
| SCHEMBL14487956 | 0.77 | TRPM2 (0.46) | TRPM2POLBCYP2C19TSHRLMNA | |
| SCHEMBL21420081 | 0.76 | MAPK1 (0.35) | TRPM2POLBCYP2C19CYP2C9MAPK1 | |
| SCHEMBL15708301 | 0.76 | TRPM2 (0.37) | TRPM2POLBCYP2C19CYP2C9MAPK1 | |
| SCHEMBL21407652 | 0.76 | TRPM2 (0.37) | TRPM2POLBCYP2C19CYP2C9MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4253366-A2 | METHODS AND INTERMEDIATES FOR PREPARING A THERAPEUTIC COMPOUND USEFUL IN THE TREATMENT OF RETROVIRIDAE VIRAL INFECTION | Gilead Sciences, Inc. (US) | 2023-10-04 | — | — | EP | disclosed |