Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | FPR2 | P25090 | 2/20 | 0.35 |
| ▸ | FPR3 | P25089 | 1/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.34 |
| ▸ | CCR3 | P51677 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18609870 | 0.90 | P2RX3 (0.41) | KMT2ANR1H2NR1H3ALDH1A1HTT | |
| SCHEMBL18607756 | 0.90 | P2RX3 (0.41) | KMT2ANR1H2NR1H3ALDH1A1HTT | |
| SCHEMBL18607754 | 0.90 | P2RX3 (0.41) | KMT2ANR1H2NR1H3ALDH1A1HTT | |
| SCHEMBL18589472 | 0.90 | P2RX3 (0.41) | KMT2ANR1H2NR1H3ALDH1A1HTT | |
| SCHEMBL26439338 | 0.89 | KMT2A (0.41) | KMT2ANR1H2NR1H3SMN1; SMN2RORC | |
| SCHEMBL22903811 | 0.83 | NR1H2 (0.38) | KMT2ANR1H2NR1H3RORCFPR2 | |
| SCHEMBL22903606 | 0.83 | NR1H2 (0.38) | KMT2ANR1H2NR1H3RORCFPR2 | |
| SCHEMBL26439349 | 0.83 | NR1H2 (0.39) | KMT2ANR1H2NR1H3RORCFPR2 | |
| SCHEMBL22903580 | 0.82 | NR1H2 (0.37) | KMT2ANR1H2NR1H3RORCFPR2 | |
| SCHEMBL22903589 | 0.82 | NR1H2 (0.37) | KMT2ANR1H2NR1H3RORCFPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11638707-B2 | Substituted amino triazoles useful as chitinase inhibitors | MOLECURE S.A. (PL) | 2023-05-02 | — | — | US | disclosed |
| CN-114174280-A | Substituted aminotriazoles useful as chitinase inhibitors | 昂科艾伦迪治疗法公司 | 2022-03-11 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11638707-B2 | Substituted amino triazoles useful as chitinase inhibitors | CHIT1, CHIA, CHI3L1 | KMT2A 2195/4885NR1H2 812/4885NR1H3 708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.