Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | ANPEP | P15144 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PEPD | P12955 | 2/20 | 0.41 |
| ▸ | VHL | P40337 | 3/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26210824 | 0.90 | CYP3A4 (0.47) | PRSS1TMPRSS15MMP2ANPEPALDH1A1 | |
| SCHEMBL26439626 | 0.87 | DPP4 (0.52) | MMP2ANPEPALDH1A1MEN1KMT2A | |
| SCHEMBL26210828 | 0.77 | DPP4 (0.53) | MMP2ANPEPALDH1A1PEPDDPP4 | |
| SCHEMBL26210873 | 0.77 | ATM (0.44) | MMP2ANPEPPEPDDPP4XPNPEP1 | |
| SCHEMBL22901988 | 0.75 | DPP4 (0.55) | KMT2ADPP4FAPDPP8DPP9 | |
| SCHEMBL25680532 | 0.73 | ALDH1A1 (0.52) | MMP2ANPEPALDH1A1MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL30574543 | 0.73 | DPP4 (0.48) | MMP2DPP4FAPDPP8DPP9 | |
| SCHEMBL15099339 | 0.72 | AGTR2 (0.61) | MMP2ANPEPALDH1A1 | |
| SCHEMBL15099380 | 0.72 | AGTR2 (0.61) | MMP2ANPEPALDH1A1 | |
| SCHEMBL15099416 | 0.72 | AGTR2 (0.61) | MMP2ANPEPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11638707-B2 | Substituted amino triazoles useful as chitinase inhibitors | MOLECURE S.A. (PL) | 2023-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11638707-B2 | Substituted amino triazoles useful as chitinase inhibitors | CHIT1, CHIA, CHI3L1 | PRSS1 37/4885TMPRSS15 31/4885MMP2 516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.