Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 4/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | AOC1 | P19801 | 5/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13838557 | 0.83 | CYP11B1 (0.43) | CYP11B2CYP11B1LMNATRPA1HTT | |
| SCHEMBL23480267 | 0.83 | CYP11B2 (0.49) | CYP11B2CYP11B1LMNAAOC1AOC3 | |
| SCHEMBL8357660 | 0.78 | AOC1 (0.59) | CYP11B2CYP11B1LMNAALDH1A1MAPT | |
| SCHEMBL526319 | 0.78 | CYP11B2 (0.45) | CYP11B2CYP11B1LMNAALDH1A1AOC1 | |
| SCHEMBL7275273 | 0.77 | SRC (0.38) | ALDH1A1GPR119POLBMAPTAOC1 | |
| SCHEMBL7275268 | 0.77 | GPR119 (0.38) | ALDH1A1GPR119POLBMAPTAOC1 | |
| SCHEMBL10679852 | 0.76 | GPR119 (0.42) | ALDH1A1GPR119POLBMAPTKDM4E | |
| SCHEMBL19308704 | 0.76 | ALDH1A1 (0.37) | CYP11B2CYP11B1LMNAALDH1A1GPR119 | |
| SCHEMBL214076 | 0.76 | — | — | |
| SCHEMBL20519199 | 0.75 | CYP11B2 (0.43) | CYP11B2CYP11B1LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105364-A1 | HETEROCYCLIC INHIBITORS OF CDC-LIKE KINASES | CURADEV PHARMA LTD (GB) | 2024-05-23 | — | — | WO | disclosed |
| WO-2023067322-A1 | TRICYCLIC GPR65 MODULATORS | Pathios Therapeutics Limited (GB) | 2023-04-27 | — | — | WO | disclosed |