SCHEMBL26445314

SCHEMBL26445314

CC(C)(C)c1ccc2c(c1)c1cccc3c4cccnc4c4cccc2c4c13

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 4/20 0.41
GRM4 Q14833 2/20 0.39
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
NPC1 O15118 1/20 0.37
HSP90AA1 P07900 1/20 0.37
PABPC1 P11940 1/20 0.36
EIF4H Q15056 1/20 0.36
GLO1 Q04760 1/20 0.36
UQCRB P14927 1/20 0.36
KDR P35968 1/20 0.35
CCR1 P32246 1/20 0.35
CCR8 P51685 1/20 0.35
ALDH1A1 P00352 2/20 0.35
KDM4E B2RXH2 1/20 0.35
TRPV1 Q8NER1 1/20 0.34
METAP2 P50579 1/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12354252 0.89 L3MBTL1 (0.47) KIF11GRM4KMT2AMEN1L3MBTL1
SCHEMBL26445268 0.77 KIF11 (0.37) KIF11GRM4KMT2AMEN1ALDH1A1
SCHEMBL26445231 0.75 L3MBTL1 (0.34) KIF11GRM4KMT2AMEN1L3MBTL1
SCHEMBL28384010 0.74 KIF11 (0.59) KIF11KMT2AMEN1L3MBTL1NPC1
SCHEMBL31326802 0.73 KIF11 (0.36) KIF11KMT2AMEN1L3MBTL1GLO1
SCHEMBL12354249 0.73 L3MBTL1 (0.44) KIF11GRM4KMT2AL3MBTL1NPC1
SCHEMBL26936078 0.71 CCR1 (0.50) KIF11GRM4KMT2AMEN1L3MBTL1
SCHEMBL22522912 0.71 PIK3CD (0.38) L3MBTL1NPC1HSP90AA1CCR1CCR8
SCHEMBL31567528 0.71 KIF11 (0.37) KIF11KMT2AMEN1L3MBTL1NPC1
SCHEMBL31567530 0.71 KIF11 (0.37) KIF11KMT2AMEN1L3MBTL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230135868-A1 ORGANIC COMPOUND, ORGANIC LIGHT-EMITTING ELEMENT, DISPLAY APPARATUS, PHOTOELECTRIC CONVERSION APPARATUS, ELECTRONIC EQUIPMENT, LIGHTING APPARATUS, MOVING BODY, AND EXPOSURE LIGHT SOURCE CANON KABUSHIKI KAISHA (JP) 2023-05-04 US disclosed
US-20230135868-A1 ORGANIC COMPOUND, ORGANIC LIGHT-EMITTING ELEMENT, DISPLAY APPARATUS, PHOTOELECTRIC CONVERSION APPARATUS, ELECTRONIC EQUIPMENT, LIGHTING APPARATUS, MOVING BODY, AND EXPOSURE LIGHT SOURCE CANON KABUSHIKI KAISHA (JP) 2023-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230135868-A1 ORGANIC COMPOUND, ORGANIC LIGHT-EMITTING ELEMENT, DISPLAY APPARATUS, PHOTOELECTRIC CONVERSION APPARATUS, ELECTRONIC EQUIPMENT, LIGHTING APPARATUS, MOVING BODY, AND EXPOSURE LIGHT SOURCE L1CAM, APOL1, TBL2 KIF11 4075/4885GRM4 497/4885KMT2A 2433/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.