Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP7 | P09237 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21795330 | 0.88 | ENPP3 (0.46) | ENPP3MMP1MMP2MMP3MMP7 | |
| SCHEMBL6561397 | 0.84 | ACHE (0.61) | ENPP3ACHEPGRHSD17B1HSD17B2 | |
| SCHEMBL25490780 | 0.84 | PTGS2 (0.53) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL18797759 | 0.82 | ACHE (0.65) | ENPP3ACHEPGRHSD17B1HSD17B2 | |
| SCHEMBL23003863 | 0.80 | ACHE (0.55) | ENPP3ACHEPGRHSD17B1HSD17B2 | |
| SCHEMBL29057032 | 0.80 | ACHE (0.55) | ENPP3ACHEPGRHSD17B1HSD17B2 | |
| SCHEMBL20689786 | 0.80 | TSHR (0.55) | ENPP3ACHEPGRHSD17B1HSD17B2 | |
| SCHEMBL5545442 | 0.80 | ACHE (0.55) | ENPP3ACHEPGRHSD17B1HSD17B2 | |
| SCHEMBL29929976 | 0.80 | ACHE (0.55) | ENPP3ACHEPGRHSD17B1HSD17B2 | |
| SCHEMBL30493472 | 0.80 | ACHE (0.55) | ENPP3ACHEPGRHSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11641775-B2 | Compounds and organic electronic devices | MERCK PATENT GMBH (DE) | 2023-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11641775-B2 | Compounds and organic electronic devices | ETV6, CYP2C19, AFF2 | ENPP3 302/4885MMP1 4778/4885MMP2 4871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.