Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | EEF2K | O00418 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13580884 | 0.84 | ALDH1A1 (0.37) | RCE1UTS2RKMT2ACA12HDAC3 | |
| SCHEMBL27783636 | 0.80 | CNR1 (0.48) | LMNAKMT2APOLBCA12MMP2 | |
| SCHEMBL27805313 | 0.79 | KMT2A (0.49) | RCE1KMT2AMEN1 | |
| SCHEMBL28786965 | 0.79 | KMT2A (0.49) | RCE1KMT2AMEN1 | |
| SCHEMBL27805310 | 0.79 | KMT2A (0.49) | RCE1KMT2AMEN1 | |
| SCHEMBL13580881 | 0.78 | NR1H4 (0.42) | LMNAKMT2ANR1H4POLBMEN1 | |
| SCHEMBL13580887 | 0.77 | KMT2A (0.59) | RCE1LMNAKMT2ANR1H4HDAC1 | |
| SCHEMBL15784727 | 0.74 | ADRB2 (0.47) | LMNAKMT2ANR1H4EEF2KMEN1 | |
| SCHEMBL15784724 | 0.74 | ADRB2 (0.47) | LMNAKMT2ANR1H4EEF2KMEN1 | |
| SCHEMBL8299228 | 0.73 | CA12 (0.43) | UTS2RCA12MMP2EEF2K |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040209928-A1 | Glucagon receptor antagonists/inverse agonists | ABBOTT LABORATORIES | 2004-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040209928-A1 | Glucagon receptor antagonists/inverse agonists | GLP1R, GPR119, GCGR | RCE1 3415/4885UTS2R 198/4885LMNA 3816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.