Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.42 |
| ▸ | PDE2A | O00408 | 2/20 | 0.41 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | EEF2K | O00418 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5782709 | 0.85 | UTS2R (0.40) | UTS2RPDE2ATRPV3PANK3PTPN5 | |
| SCHEMBL2859953 | 0.81 | UTS2R (0.37) | CA12CA1MMP2UTS2RPDE2A | |
| SCHEMBL84043 | 0.76 | PDE2A (0.53) | PDE2APTPN5KIF11 | |
| SCHEMBL1259754 | 0.74 | TRPV3 (0.48) | CA12CA1MMP2TRPV3KIF11 | |
| Ammonia Solution, Strong SCHEMBL27642816 | 0.74 | PDE2A (0.52) | PDE2APTPN5KIF11 | |
| SCHEMBL2644697 | 0.73 | RCE1 (0.38) | CA12MMP2UTS2REEF2K | |
| SCHEMBL27634082 | 0.72 | UTS2R (0.40) | UTS2RPDE2AGCGRPANK3KIF11 | |
| SCHEMBL4779882 | 0.72 | TRPV3 (0.45) | PDE2ATRPV3P2RX3 | |
| SCHEMBL855311 | 0.72 | FFAR1 (0.55) | MAPT | |
| SCHEMBL5424944 | 0.71 | CCNT1 (0.50) | CA12CA1MMP2TRPV3KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005013985-A1 | TREATMENT FOR ALZHEIMER'S DISEASE AND RELATED CONDITIONS | MERCK SHARP & DOHME LIMITED (GB) | 2005-02-17 | — | — | WO | disclosed |