Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 4/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | KDM5C | P41229 | 2/20 | 0.37 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.37 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13631859 | 1.00 | ECE1 (0.50) | ECE1FAAHCNR1CNR2GABRR1 | |
| SCHEMBL385127 | 0.91 | ECE1 (0.58) | ECE1FAAHCNR1CNR2GABRR1 | |
| SCHEMBL3185096 | 0.88 | ATM (0.46) | GABRR1ITGB3ITGA2BKDM4ETSHR | |
| SCHEMBL7444117 | 0.86 | PRMT1 (0.52) | ITGB3ITGA2BTSHRLMNATHRB | |
| Oxalic Acid SCHEMBL28780170 | 0.85 | ECE1 (0.52) | ECE1FAAHCNR1CNR2GABRR1 | |
| SCHEMBL23890277 | 0.83 | TERT (0.36) | ECE1TERTCA1CA2 | |
| SCHEMBL391787 | 0.82 | GLRA1 (0.43) | FAAHKDM4EGLRA1SLC6A9OR51E2 | |
| SCHEMBL6674893 | 0.82 | GLRA1 (0.43) | FAAHKDM4EGLRA1SLC6A9OR51E2 | |
| SCHEMBL1402291 | 0.82 | GLRA1 (0.43) | FAAHKDM4EGLRA1SLC6A9OR51E2 | |
| SCHEMBL391028 | 0.82 | GLRA1 (0.43) | FAAHKDM4EGLRA1SLC6A9OR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170283466-A1 | METHOD FOR PREPARING MULTIPLE ANTIGEN GLYCOPEPTIDE CARBOHYDRATE CONJUGATES | INSTITUT PASTEUR (FR) | 2017-10-05 | — | — | US | disclosed |
| US-20140378652-A9 | METHOD FOR PREPARING MULTIPLE ANTIGEN GLYCOPEPTIDE CARBOHYDRATE CONJUGATES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-12-25 | — | — | US | disclosed |
| US-20140171618-A1 | METHOD FOR PREPARING MULTIPLE ANTIGEN GLYCOPEPTIDE CARBOHYDRATE CONJUGATES | CENTRE MATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-06-19 | — | — | US | disclosed |
| CN-101821244-B | Phenobarbital derivatives useful in immunoassay | HOFFMANN LA ROCHE | 2012-09-05 | — | — | CN | disclosed |
| US-8133743-B2 | Phenobarbital derivatives useful in immunoassay | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2012-03-13 | — | — | US | disclosed |
| CN-101821244-A | Phenobarbital derivatives useful in immunoassay | HOFFMANN LA ROCHE | 2010-09-01 | — | — | CN | disclosed |
| CN-101472945-A | Saquinavir derivatives useful in immunoassay | ROCHE DIAGNOSTICS GMBH (CH) | 2009-07-01 | — | — | CN | disclosed |
| US-20090104713-A1 | Phenobarbital derivatives useful in immunoassay | ROCHE DIAGNOSTICS OPERATIONS, INC. | 2009-04-23 | — | — | US | disclosed |
| EP-1824883-A2 | SAQUINAVIR DERIVATIVES USEFUL IN IMMUNOASSAY | Roche Diagnostics GmbH (DE) | 2007-08-29 | — | — | EP | disclosed |
| WO-2006061217-A2 | SAQUINAVIR DERIVATIVES USEFUL IN IMMUNOASSAY | ROCHE DIAGNOSTICS GMBH (DE) | 2006-06-15 | — | — | WO | disclosed |
| US-6992177-B1 | Saquinavir derivatives useful in immunoassay | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2006-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090104713-A1 | Phenobarbital derivatives useful in immunoassay | PGM2, CYP4F2, CYP3A7 | ECE1 2881/4885FAAH 623/4885CNR1 2187/4885 |
| US-20170283466-A1 | METHOD FOR PREPARING MULTIPLE ANTIGEN GLYCOPEPTIDE CARBOHYDRATE CONJUGATES | MICA, NGLY1, CD4 | ECE1 1965/4885FAAH 3921/4885CNR1 3865/4885 |
| US-20140378652-A9 | METHOD FOR PREPARING MULTIPLE ANTIGEN GLYCOPEPTIDE CARBOHYDRATE CONJUGATES | CD4, MICA, MUC1 | ECE1 1628/4885FAAH 3477/4885CNR1 3579/4885 |
| US-20140171618-A1 | METHOD FOR PREPARING MULTIPLE ANTIGEN GLYCOPEPTIDE CARBOHYDRATE CONJUGATES | CD4, MICA, MUC1 | ECE1 1628/4885FAAH 3477/4885CNR1 3579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.