SCHEMBL26455366

SCHEMBL26455366

CN(C)C(=O)CC[Si](C)(C)F

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
CHRNB2 P17787 1/20 0.39
CHRNB4 P30926 1/20 0.39
CHRNA4 P43681 1/20 0.39
HSD17B10 Q99714 1/20 0.35
NR4A1 P22736 1/20 0.33
NR4A2 P43354 1/20 0.33
NR4A3 Q92570 1/20 0.33
GLA P06280 1/20 0.31
NPC1 O15118 2/20 0.30
RAB9A P51151 2/20 0.30
LMNA P02545 1/20 0.30
CYP1A2 P05177 1/20 0.30
TSHR P16473 1/20 0.30
CYP2C19 P33261 1/20 0.30
PHF8 Q9UPP1 1/20 0.30
KDM2A Q9Y2K7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26454755 0.88 ALDH1A1 (0.44) ALDH1A1CHRNB2CHRNB4CHRNA4HSD17B10
SCHEMBL26454517 0.85 ALDH1A1 (0.46) ALDH1A1CHRNB2CHRNB4CHRNA4HSD17B10
SCHEMBL26455367 0.76 LMNA (0.56) ALDH1A1NPC1RAB9ALMNATSHR
SCHEMBL1191256 0.74 ALDH1A1 (0.63) ALDH1A1CHRNB2CHRNB4CHRNA4HSD17B10
SCHEMBL23701014 0.74
SCHEMBL26455372 0.74
SCHEMBL4056869 0.70
SCHEMBL2033454 0.70
SCHEMBL131476 0.69 ALDH1A1 (0.74) ALDH1A1CHRNB2CHRNB4CHRNA4LMNA
SCHEMBL5948495 0.69 ALDH1A1 (0.74) ALDH1A1CHRNB2CHRNB4CHRNA4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230127105-A1 Nonaqueous Electrolytic Solution and Nonaqueous Electrolytic Solution Battery MITSUBISHI CHEMICAL CORPORATION (JP) 2023-04-27 US disclosed
US-20230127105-A1 Nonaqueous Electrolytic Solution and Nonaqueous Electrolytic Solution Battery MITSUBISHI CHEMICAL CORPORATION (JP) 2023-04-27 US disclosed