Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP2 | Q9HC62 | 6/20 | 0.70 |
| ▸ | SENP1 | Q9P0U3 | 6/20 | 0.70 |
| ▸ | SENP3 | Q9H4L4 | 5/20 | 0.70 |
| ▸ | SUMO2 | P61956 | 4/20 | 0.70 |
| ▸ | SUMO1 | P63165 | 4/20 | 0.70 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.70 |
| ▸ | GLO1 | Q04760 | 4/20 | 0.51 |
| ▸ | RAD1 | O60671 | 1/20 | 0.47 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.47 |
| ▸ | ATIC | P31939 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26459377 | 0.95 | SENP2 (0.76) | SENP2SENP1SENP3SUMO2SUMO1 | |
| SCHEMBL26459374 | 0.88 | SENP2 (0.91) | SENP2SENP1SENP3SUMO2SUMO1 | |
| SCHEMBL29473545 | 0.82 | SENP2 (1.00) | SENP2SENP1SENP3SUMO2SUMO1 | |
| SCHEMBL6339124 | 0.82 | SENP2 (1.00) | SENP2SENP1SENP3SUMO2SUMO1 | |
| SCHEMBL29554795 | 0.82 | SENP2 (1.00) | SENP2SENP1SENP3SUMO2SUMO1 | |
| SCHEMBL3958375 | 0.82 | SENP2 (1.00) | SENP2SENP1SENP3SUMO2SUMO1 | |
| SCHEMBL26460858 | 0.82 | SENP2 (1.00) | SENP2SENP1SENP3SUMO2SUMO1 | |
| SCHEMBL26459366 | 0.82 | SENP2 (0.71) | SENP2SENP1SENP3SUMO2SUMO1 | |
| SCHEMBL13856931 | 0.80 | SENP2 (0.67) | SENP2SENP1SENP3SUMO2SUMO1 | |
| SCHEMBL18586759 | 0.78 | SENP2 (0.89) | SENP2SENP1SENP3SUMO2SUMO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230127304-A1 | NEW INHIBITORS FOR THE KEAP1-NRF2 PROTEIN-PROTEIN INTERACTION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230127304-A1 | NEW INHIBITORS FOR THE KEAP1-NRF2 PROTEIN-PROTEIN INTERACTION | KEAP1, HMOX1, NFE2L2 | SENP2 2951/4885SENP1 2007/4885SENP3 2753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.