SCHEMBL26460725

SCHEMBL26460725

CC1(C)c2ccccc2-c2c1cc(N(c1ccccc1)c1ccc(-c3ccccc3)cc1)c1c2[nH]c2ccccc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHEK1 O14757 3/20 0.37
PARP1 P09874 2/20 0.34
CDK4 P11802 5/20 0.33
CCND1 P24385 5/20 0.33
CDK5 Q00535 2/20 0.33
CDK5R1 Q15078 2/20 0.33
GSK3A P49840 1/20 0.33
GSK3B P49841 1/20 0.33
CAMK2B Q13554 3/20 0.33
CAMK2G Q13555 3/20 0.33
CAMK2D Q13557 3/20 0.33
CAMK2A Q9UQM7 3/20 0.33
MEN1 O00255 2/20 0.33
MAPT P10636 2/20 0.33
KMT2A Q03164 2/20 0.33
PRKD3 O94806 2/20 0.33
PRKCG P05129 2/20 0.33
PRKCB P05771 2/20 0.33
PRKCA P17252 2/20 0.33
PRKCH P24723 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13776690 0.79 PDK2 (0.30) HTR2B
SCHEMBL13776681 0.79 PDK2 (0.31) HTR2B
SCHEMBL13776707 0.79 PDK2 (0.31) HTR2B
SCHEMBL13776682 0.79 MLNR (0.31) HTR2B
SCHEMBL13776684 0.79 PDK2 (0.31)
SCHEMBL22402000 0.77 PARP14 (0.33) CDK4CCND1CCNE2CCNE1CDK2
SCHEMBL24730495 0.77 CHEK1 (0.44) CHEK1PARP1CDK4CCND1CDK5
SCHEMBL25954138 0.77 ALOX5 (0.32)
SCHEMBL18012352 0.76 CRHR1 (0.30)
SCHEMBL15840240 0.76 PGR (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230134334-A1 AMINE COMPOUND HAVING FUSED RING, AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME SFC CO., LTD (KR) 2023-05-04 US disclosed
US-20230134334-A1 AMINE COMPOUND HAVING FUSED RING, AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME SFC CO., LTD (KR) 2023-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230134334-A1 AMINE COMPOUND HAVING FUSED RING, AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME EML4, SLC18A2, TYR CHEK1 3544/4885PARP1 2631/4885CDK4 130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.