Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATIC | P31939 | 3/20 | 0.52 |
| ▸ | FBP1 | P09467 | 2/20 | 0.52 |
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.51 |
| ▸ | DNPH1 | O43598 | 3/20 | 0.51 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.51 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.51 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.51 |
| ▸ | LDHA | P00338 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
| ▸ | SRC | P12931 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.51 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.51 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8840654 | 0.89 | ATIC (0.52) | ATICFBP1TAS1R3TAS1R1DNPH1 | |
| SCHEMBL2449672 | 0.89 | ATIC (0.56) | ATICFBP1TAS1R3TAS1R1DNPH1 | |
| SCHEMBL8018540 | 0.84 | ATIC (0.48) | ATICFBP1TAS1R3TAS1R1DNPH1 | |
| SCHEMBL41683 | 0.83 | KDM4E (0.47) | ADORA1SMN1; SMN2 | |
| SCHEMBL6704190 | 0.82 | ATIC (0.57) | ATICFBP1TAS1R3TAS1R1DNPH1 | |
| SCHEMBL625829 | 0.81 | P2RY1 (0.57) | P2RY2TRPM2SRCP2RY1SMN1; SMN2 | |
| SCHEMBL2448088 | 0.81 | P2RY1 (0.48) | ATICFBP1ADORA1P2RY1P2RY11 | |
| SCHEMBL2919342 | 0.79 | ATIC (0.49) | ATICFBP1TAS1R3TAS1R1DNPH1 | |
| SCHEMBL9549302 | 0.79 | ATIC (0.49) | ATICFBP1TAS1R3TAS1R1DNPH1 | |
| SCHEMBL8028076 | 0.78 | P2RX3 (0.48) | P2RY2SRCP2RY1SMN1; SMN2P2RY11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4507089-A | Mechanical support module for nucleic acid | TCHUEMPE TCHUENTE GERMAIN (FR) | 1985-03-26 | — | — | US | claimed |
| CN-114585742-A | Treatment of | 牛津大学创新有限公司 | 2022-06-03 | — | — | CN | disclosed |
| US-8133724-B2 | Human androgen receptor alternative splice variants as biomarkers and therapeutic targets | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2012-03-13 | — | — | US | disclosed |
| US-4507089-A | Mechanical support module for nucleic acid | TCHUEMPE TCHUENTE GERMAIN (FR) | 1985-03-26 | — | — | US | disclosed |