Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATIC | P31939 | 3/20 | 0.49 |
| ▸ | FBP1 | P09467 | 2/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.49 |
| ▸ | GART | P22102 | 1/20 | 0.48 |
| ▸ | DNPH1 | O43598 | 2/20 | 0.48 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.48 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.48 |
| ▸ | LDHA | P00338 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.48 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.48 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.48 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18062492 | 0.85 | MAPT (0.45) | SMN1; SMN2 | |
| SCHEMBL2919342 | 0.82 | ATIC (0.49) | ATICFBP1TAS1R3TAS1R1GART | |
| SCHEMBL6704190 | 0.79 | ATIC (0.57) | ATICFBP1TAS1R3TAS1R1GART | |
| SCHEMBL264616 | 0.79 | ATIC (0.52) | ATICFBP1TAS1R3TAS1R1GART | |
| SCHEMBL8840654 | 0.79 | ATIC (0.52) | ATICFBP1TAS1R3TAS1R1GART | |
| SCHEMBL2449672 | 0.79 | ATIC (0.56) | ATICFBP1TAS1R3TAS1R1GART | |
| SCHEMBL8018540 | 0.78 | ATIC (0.48) | ATICFBP1TAS1R3TAS1R1GART | |
| SCHEMBL3967635 | 0.75 | ATIC (0.56) | ATICFBP1TAS1R3TAS1R1GART | |
| SCHEMBL5721746 | 0.74 | P2RX3 (0.52) | SRCP2RY2P2RY1SMN1; SMN2P2RY11 | |
| SCHEMBL8028076 | 0.71 | P2RX3 (0.48) | SRCP2RY2P2RY1SMN1; SMN2P2RY11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232967-B1 | COMPETITIVE HOMOGENEOUS ASSAY | AMOCO CORPORATION (US) | 1993-04-28 | — | — | EP | claimed |