Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 5/20 | 0.48 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.48 |
| ▸ | RNASEL | Q05823 | 3/20 | 0.47 |
| ▸ | P2RY1 | P47900 | 5/20 | 0.46 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.46 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.46 |
| ▸ | P2RY6 | Q15077 | 4/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.46 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.46 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.46 |
| ▸ | P2RY2 | P41231 | 5/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8018540 | 0.93 | ATIC (0.48) | RNASELP2RY1P2RY11P2RY2SRC | |
| SCHEMBL8029815 | 0.82 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL3512412 | 0.78 | NT5E (0.53) | P2RX3P2RX2RNASELP2RY1ENPP1 | |
| SCHEMBL625829 | 0.78 | P2RY1 (0.57) | P2RX3P2RX2RNASELP2RY1ENPP1 | |
| SCHEMBL264616 | 0.78 | ATIC (0.52) | RNASELP2RY1P2RY6P2RY11P2RY2 | |
| SCHEMBL5721746 | 0.76 | P2RX3 (0.52) | P2RX3P2RX2RNASELP2RY1ENPP1 | |
| SCHEMBL4377679 | 0.75 | RNASEL (0.51) | P2RX3P2RX2RNASELP2RY1ENPP1 | |
| SCHEMBL8028285 | 0.74 | MEN1 (0.43) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL6704190 | 0.72 | ATIC (0.57) | P2RX3P2RX2RNASELP2RY1P2RX4 | |
| SCHEMBL8840654 | 0.72 | ATIC (0.52) | RNASELP2RY1P2RY6P2RY11P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6130324-A | HAVING MODIFIED PURINE NUCLEOTIDES; VIRICIDES AGAINST HUMAN IMMUNODEFICIENCY VIRUS AND HUMAN CYTOMEGALOVIRUS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2000-10-10 | — | — | US | claimed |
| US-6130324-A | HAVING MODIFIED PURINE NUCLEOTIDES; VIRICIDES AGAINST HUMAN IMMUNODEFICIENCY VIRUS AND HUMAN CYTOMEGALOVIRUS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2000-10-10 | — | — | US | disclosed |