Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.54 |
| ▸ | IDH1 | O75874 | 3/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471903 | 0.81 | PTGS1 (0.46) | ESR1ESR2 | |
| SCHEMBL7467558 | 0.81 | ESR1 (0.44) | ESR1ESR2IDH1 | |
| SCHEMBL6234291 | 0.80 | ESR1 (0.83) | ESR1ESR2IDH1THRATHRB | |
| SCHEMBL11177663 | 0.80 | ESR1 (0.83) | ESR1ESR2IDH1THRATHRB | |
| SCHEMBL4616641 | 0.79 | APP (0.50) | LTA4H | |
| SCHEMBL3918695 | 0.78 | ESR1 (0.50) | ESR1ESR2IDH1CA1CA2 | |
| SCHEMBL7465577 | 0.78 | LTA4H (0.53) | ESR1ESR2IDH1CA2LTA4H | |
| SCHEMBL5527320 | 0.78 | ESR1 (0.61) | ESR1ESR2IDH1THRATHRB | |
| SCHEMBL49999 | 0.77 | — | — | |
| SCHEMBL16584850 | 0.77 | LOXL2 (0.47) | ESR1ESR2IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023073115-A1 | PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2023-05-04 | — | — | WO | disclosed |