SCHEMBL26465757

SCHEMBL26465757

CCOC(C)CCCCOCCO

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
THRB P10828 1/20 0.48
HTT P42858 1/20 0.48
MAPT P10636 1/20 0.48
TSHR P16473 2/20 0.48
ALDH1A1 P00352 1/20 0.43
MAPK1 P28482 1/20 0.39
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33
USP2 O75604 1/20 0.32
LMNA P02545 1/20 0.31
EPHX2 P34913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25779343 0.86 ALDH1A1 (0.48) MEN1KMT2ATHRBHTTMAPT
SCHEMBL25779336 0.83 MEN1 (0.42) MEN1KMT2ATHRBHTTMAPT
SCHEMBL29892792 0.82 EPHX2 (0.33) MEN1KMT2ATSHRALDH1A1CYP4F2
SCHEMBL22890965 0.81 TSHR (0.55) MEN1KMT2ATHRBHTTMAPT
SCHEMBL9317960 0.81 LMNA (0.38) MEN1KMT2ATHRBTSHRALDH1A1
SCHEMBL25779354 0.81 MEN1 (0.39) MEN1KMT2ATHRBHTTMAPT
SCHEMBL491121 0.80 MEN1 (0.52) MEN1KMT2ATHRBHTTMAPT
SCHEMBL11245006 0.79 LMNA (0.40) MEN1KMT2ATHRBTSHRALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL4830560 0.79 ALDH1A1 (0.50) MEN1KMT2ATHRBHTTMAPT
SCHEMBL29521238 0.79 MEN1 (0.57) MEN1KMT2ATHRBHTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230139745-A1 NON-PEPTIDIC POLYMERIC LINKER COMPOUND, CONJUGATE COMPRISING SAME LINKER COMPOUND, AND METHODS FOR PREPARING SAME LINKER COMPOUND AND CONJUGATE HANMI PHARM. CO., LTD. (KR) 2023-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230139745-A1 NON-PEPTIDIC POLYMERIC LINKER COMPOUND, CONJUGATE COMPRISING SAME LINKER COMPOUND, AND METHODS FOR PREPARING SAME LINKER COMPOUND AND CONJUGATE FCGR1A, FCGR3B, FCGR2A MEN1 981/4885KMT2A 3032/4885THRB 2973/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.