Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26465080 | 0.89 | CACNA1H (0.56) | CACNA1HMEN1KMT2A | |
| SCHEMBL26466006 | 0.88 | CACNA1H (0.53) | CACNA1HMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL26465563 | 0.84 | CACNA1H (0.42) | CACNA1HMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL26465689 | 0.84 | CACNA1H (0.54) | CACNA1HMEN1KMT2AATMDRD4 | |
| SCHEMBL26466097 | 0.82 | CACNA1H (0.45) | CACNA1HMEN1KMT2AALDH1A1 | |
| SCHEMBL26465564 | 0.81 | CACNA1H (0.43) | CACNA1HMEN1KMT2AATMALDH1A1 | |
| SCHEMBL26465688 | 0.80 | HPGD (0.53) | CACNA1HMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL26465813 | 0.80 | MAPT (0.43) | CACNA1HALDH1A1SMN1; SMN2 | |
| SCHEMBL26465825 | 0.80 | ALDH1A1 (0.44) | CACNA1HMEN1KMT2AATMALDH1A1 | |
| SCHEMBL26466009 | 0.80 | CACNA1H (0.49) | CACNA1HMEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192669-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING A PIPERAZINE OR 1,4-DIAZEPANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |