Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 11/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26464490 | 0.89 | CACNA1H (0.54) | CACNA1HCACNA1GCACNA1I | |
| SCHEMBL26465573 | 0.87 | CACNA1H (0.72) | CACNA1HMEN1KMT2ALMNAACKR3 | |
| SCHEMBL26465704 | 0.86 | CACNA1H (0.51) | CACNA1HCACNA1GCACNA1I | |
| SCHEMBL26498774 | 0.84 | ALDH1A1 (0.53) | CACNA1HMEN1KMT2ALMNAATM | |
| SCHEMBL26466012 | 0.84 | CACNA1H (0.45) | CACNA1HMEN1KMT2AATMDRD4 | |
| SCHEMBL26465838 | 0.83 | CACNA1H (0.55) | CACNA1HCACNA1GCACNA1IDRD4ALDH1A1 | |
| SCHEMBL26463608 | 0.82 | CACNA1H (0.56) | CACNA1HCACNA1GCACNA1I | |
| SCHEMBL26464783 | 0.82 | CACNA1H (0.46) | CACNA1HKMT2ACACNA1GCACNA1I | |
| SCHEMBL26465699 | 0.80 | HPGD (0.55) | CACNA1HMEN1KMT2ALMNAMAPT | |
| SCHEMBL26465810 | 0.79 | CACNA1H (0.47) | CACNA1HLMNAMAPTCACNA1GALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192669-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING A PIPERAZINE OR 1,4-DIAZEPANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |