Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30296302 | 1.00 | KDM4E (0.30) | KDM4EKMT2AL3MBTL1 | |
| SCHEMBL713697 | 0.80 | GAA (0.43) | KDM4EKMT2AL3MBTL1 | |
| SCHEMBL713696 | 0.80 | GAA (0.43) | KDM4EKMT2AL3MBTL1 | |
| SCHEMBL713699 | 0.80 | GAA (0.43) | KDM4EKMT2AL3MBTL1 | |
| SCHEMBL713698 | 0.80 | GAA (0.43) | KDM4EKMT2AL3MBTL1 | |
| SCHEMBL22159263 | 0.79 | KDM4E (0.40) | KDM4EKMT2AL3MBTL1 | |
| SCHEMBL22158835 | 0.79 | ALDH1A1 (0.52) | KDM4EKMT2AL3MBTL1 | |
| SCHEMBL22158834 | 0.79 | ALDH1A1 (0.52) | KDM4EKMT2AL3MBTL1 | |
| SCHEMBL22159261 | 0.79 | KDM4E (0.40) | KDM4EKMT2AL3MBTL1 | |
| SCHEMBL17601058 | 0.79 | KDM4E (0.40) | KDM4EKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230373989-A1 | N-PHENYLAMINOCARBONYL PYRIDINO-, PYRIMIDINO AND BENZO-TROPANES AS MODULATORS OF GPR65 | Pathios Therapeutics Limited (GB) | 2023-11-23 | — | — | US | disclosed |
| US-20230373989-A1 | N-PHENYLAMINOCARBONYL PYRIDINO-, PYRIMIDINO AND BENZO-TROPANES AS MODULATORS OF GPR65 | Pathios Therapeutics Limited (GB) | 2023-11-23 | — | — | US | disclosed |
| CN-116783195-A | N-phenylaminocarbonyl pyridinyl-, pyrimidinyl and benzo-tropanes as modulators of GPR65 | 帕蒂奥斯治疗有限公司 | 2023-09-19 | — | — | CN | disclosed |
| WO-2023067322-A1 | TRICYCLIC GPR65 MODULATORS | Pathios Therapeutics Limited (GB) | 2023-04-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230373989-A1 | N-PHENYLAMINOCARBONYL PYRIDINO-, PYRIMIDINO AND BENZO-TROPANES AS MODULATORS OF GPR65 | GPR65, GPR55, GPR68 | KDM4E 3200/4885KMT2A 2894/4885L3MBTL1 3791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.