Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 4/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | WNT3A | P56704 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26466389 | 1.00 | CACNA1H (0.40) | CACNA1HLTA4HMEN1KMT2ACRHBP | |
| SCHEMBL26465563 | 0.89 | CACNA1H (0.42) | CACNA1HMEN1KMT2ACRHBPCRHR2 | |
| SCHEMBL26466903 | 0.89 | CACNA1H (0.50) | CACNA1HLTA4HMEN1KMT2AEPHX2 | |
| SCHEMBL26464769 | 0.86 | LMNA (0.44) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL26467004 | 0.85 | CACNA1H (0.36) | CACNA1HLTA4H | |
| SCHEMBL26466415 | 0.84 | CACNA1H (0.53) | CACNA1HLTA4HMEN1KMT2AALDH1A1 | |
| SCHEMBL26466233 | 0.84 | CACNA1H (0.53) | CACNA1HLTA4HMEN1KMT2AALDH1A1 | |
| SCHEMBL26466406 | 0.83 | CACNA1H (0.54) | CACNA1HLTA4HMEN1KMT2ACRHBP | |
| SCHEMBL26466222 | 0.83 | CACNA1H (0.54) | CACNA1HLTA4HMEN1KMT2ACRHBP | |
| SCHEMBL26466237 | 0.83 | CACNA1H (0.54) | CACNA1HLTA4HMEN1KMT2ACRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192669-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING A PIPERAZINE OR 1,4-DIAZEPANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |