Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 3/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26467001 | 0.90 | LTA4H (0.38) | CACNA1HLTA4HKMT2AMAPTMEN1 | |
| SCHEMBL26465703 | 0.90 | CACNA1H (0.40) | CACNA1HKMT2AMAPTMEN1EPHX2 | |
| SCHEMBL26467004 | 0.89 | CACNA1H (0.36) | CACNA1HLTA4H | |
| SCHEMBL26466916 | 0.84 | SIGMAR1 (0.42) | CACNA1HLTA4HMAPTHPGD | |
| SCHEMBL26466243 | 0.84 | HPGD (0.49) | CACNA1HKMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL26466594 | 0.84 | HPGD (0.49) | CACNA1HKMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL26466250 | 0.84 | HPGD (0.49) | CACNA1HKMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL26466596 | 0.83 | CACNA1H (0.40) | CACNA1HLTA4HKMT2AMAPTMEN1 | |
| SCHEMBL26466389 | 0.83 | CACNA1H (0.40) | CACNA1HLTA4HKMT2AMAPTMEN1 | |
| SCHEMBL26466907 | 0.83 | CACNA1H (0.40) | CACNA1HLTA4HKMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192669-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING A PIPERAZINE OR 1,4-DIAZEPANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |