Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8060263 | 0.85 | CHRNB2 (0.35) | CHRNB2CHRNA4CHRNB4CHRNA3TDP1 | |
| SCHEMBL26468771 | 0.84 | ELANE (0.34) | SPHK1TSHR | |
| SCHEMBL1840177 | 0.83 | SPHK1 (0.46) | SPHK1 | |
| SCHEMBL26468779 | 0.83 | — | — | |
| SCHEMBL1370603 | 0.83 | SPHK1 (0.46) | SPHK1 | |
| SCHEMBL1370602 | 0.83 | SPHK1 (0.46) | SPHK1 | |
| SCHEMBL26468788 | 0.83 | — | — | |
| SCHEMBL2896396 | 0.81 | — | — | |
| SCHEMBL2880294 | 0.81 | — | — | |
| SCHEMBL14692211 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023072143-A1 | CAMPTOTHECIN DERIVATIVE INTERMEDIATE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海弼领生物技术有限公司 | 2023-05-04 | — | — | WO | disclosed |