Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 2/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26468771 | 0.90 | ELANE (0.34) | SPHK1IDH1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL26468519 | 0.81 | CHRNB2 (0.34) | SPHK1 | |
| SCHEMBL26468779 | 0.77 | — | — | |
| SCHEMBL1840177 | 0.77 | SPHK1 (0.46) | SPHK1SMN1; SMN2 | |
| SCHEMBL1370602 | 0.77 | SPHK1 (0.46) | SPHK1SMN1; SMN2 | |
| SCHEMBL1370603 | 0.77 | SPHK1 (0.46) | SPHK1SMN1; SMN2 | |
| SCHEMBL26468788 | 0.77 | — | — | |
| SCHEMBL2880294 | 0.76 | — | — | |
| SCHEMBL14692211 | 0.76 | — | — | |
| SCHEMBL12164706 | 0.71 | LMNA (0.43) | SPHK1PRKCALMNAPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023072143-A1 | CAMPTOTHECIN DERIVATIVE INTERMEDIATE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海弼领生物技术有限公司 | 2023-05-04 | — | — | WO | disclosed |