Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26471057 | 0.94 | KDM4E (0.34) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL26470796 | 0.90 | KDM4E (0.38) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL20783225 | 0.88 | LMNA (0.41) | KMT2AMAPTKDM4ELMNAPOLB | |
| SCHEMBL22200884 | 0.88 | LMNA (0.41) | KMT2AMAPTKDM4ELMNAPOLB | |
| SCHEMBL26470320 | 0.87 | CYP11B2 (0.42) | MAPTKDM4ELMNAPOLBCYP11B1 | |
| SCHEMBL30841590 | 0.83 | ALDH1A1 (0.38) | RECQLALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL31518993 | 0.83 | ALDH1A1 (0.38) | RECQLALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL26470794 | 0.83 | KDM4E (0.33) | ALDH1A1MAPTKDM4ELMNAPOLB | |
| SCHEMBL26623065 | 0.80 | HDAC1 (0.36) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL26623089 | 0.79 | HDAC1 (0.35) | ALDH1A1MEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023072143-A1 | CAMPTOTHECIN DERIVATIVE INTERMEDIATE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海弼领生物技术有限公司 | 2023-05-04 | — | — | WO | disclosed |