Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 2/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.36 |
| ▸ | PPID | Q08752 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20562704 | 0.89 | UCHL1 (0.38) | ALDH1A1P2RX7UCHL1PKM | |
| SCHEMBL26094241 | 0.85 | UCHL1 (0.37) | P2RX7UCHL1PKM | |
| SCHEMBL11105 | 0.83 | PKM (0.44) | L3MBTL1ALDH1A1UCHL1PPIDPKM | |
| SCHEMBL12602988 | 0.82 | ALDH1A1 (0.47) | L3MBTL1ALDH1A1MAPK1DGAT1LMNA | |
| SCHEMBL30413353 | 0.81 | PTGER4 (0.41) | PTGER4PTGER3PTGER2PTGER1ALDH1A1 | |
| SCHEMBL19830896 | 0.80 | DGAT1 (0.48) | L3MBTL1ALDH1A1MAPK1DGAT1LMNA | |
| SCHEMBL134963 | 0.79 | FFAR4 (0.41) | L3MBTL1ALDH1A1MAPK1LMNAUCHL1 | |
| SCHEMBL477979 | 0.78 | PTGER4 (0.48) | PRMT5PTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL23219214 | 0.77 | PRMT5 (0.47) | PRMT5PTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL29853178 | 0.77 | PRMT5 (0.47) | PRMT5PTGER4PTGER3PTGER2PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118176187-A | Condensed ring compound, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2024-06-11 | — | — | CN | disclosed |