SCHEMBL2647486

SCHEMBL2647486

CC(O)c1ccccc1-c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.44
HSD17B10 Q99714 2/20 0.44
HPGD P15428 1/20 0.44
BCL2L1 Q07817 1/20 0.44
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
BACE1 P56817 1/20 0.41
PDCD1 Q15116 1/20 0.39
CD274 Q9NZQ7 1/20 0.39
CYP2A6 P11509 1/20 0.39
MAPK1 P28482 1/20 0.39
TAS1R3 Q7RTX0 1/20 0.39
TAS1R1 Q7RTX1 1/20 0.39
ADRB2 P07550 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3854616 0.93 ALDH1A1 (0.43) ALDH1A1HSD17B10HPGDBCL2L1CA12
SCHEMBL5907397 0.85 GABRA1 (0.44) ALDH1A1HPGDCA1CA2MAPK1
SCHEMBL11331364 0.85 MEN1 (0.43) ALDH1A1CA12CA1CA2CA9
SCHEMBL9513577 0.85 ABL1 (0.48) BCL2L1CA12CA1CA2CA9
SCHEMBL16409728 0.84 SLC6A4 (0.45) ALDH1A1CA12CA1CA2CA9
SCHEMBL4058252 0.84 SLC6A4 (0.45) HSD17B10HPGDCA12CA1CA2
SCHEMBL16731883 0.84 SLC6A4 (0.45) ALDH1A1CA12CA1CA2CA9
SCHEMBL3398674 0.84 SLC6A3 (0.44) ALDH1A1HPGDCA12CA1CA2
SCHEMBL5907403 0.84 RECQL (0.39) ALDH1A1HSD17B10HPGDBCL2L1CA12
SCHEMBL15224150 0.84 HNF4A (0.47) ALDH1A1HSD17B10HPGDBCL2L1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-1079138-A None JP disclosed
JP-1242544-A None JP disclosed
JP-1163155-A None JP disclosed
JP-1242552-A None JP disclosed
CN-115193393-A Chiral stationary phase material, preparation method and chromatographic column 同济大学 2022-10-18 CN disclosed
WO-2021112194-A1 COMPOSITION FOR FORMING UNDERLAYER FILM FOR LITHOGRAPHY, UNDERLAYER FILM FOR LITHOGRAPHY, RESIST PATTERN FORMING METHOD, CIRCUIT PATTERN FORMING METHOD, OLIGOMER, AND PURIFICATION METHOD 三菱瓦斯化学株式会社 2021-06-10 WO disclosed
CN-102317757-B OPTICALLY ACTIVE FUNCTIONAL FLUID MARKERS LUBRIZOL CORP 2015-02-18 CN disclosed
US-8717565-B2 Optically active functional fluid markers THE LUBRIZOL CORPORATION (US) 2014-05-06 US disclosed
CN-103709033-A o-phenyl phenoxyethyl acrylate preparation method SHANGHAI WEIKAI CHEMICALS CO 2014-04-09 CN disclosed
CN-102317757-A Optical activity functional fluid label LUBRIZOL CORP 2012-01-11 CN disclosed
CN-1046507-C Heterocyclic compounds for the treatment of central nervous system and cardiovascular diseases UPJOHN CO (US) 1999-11-17 CN disclosed
EP-0934274-A1 SUBSTITUTED PYRIDINES AND BIPHENYLS AS ANTI-HYPERCHOLESTERINEMIC, ANTI-HYPERLIPOPROTEINEMIC AND ANTI-HYPERGLYCEMIC AGENTS Bayer Corporation (US) 1999-08-11 EP disclosed
WO-1998004528-A2 SUBSTITUTED PYRIDINES AND BIPHENYLS AS ANTI-HYPERCHOLESTERINEMIC, ANTI-HYPERLIPOPROTEINEMIC AND ANTI-HYPERGLYCEMIC AGENTS BAYER CORPORATION (US) 1998-02-05 WO disclosed
CN-1139431-A Heterocyclic compounds for the treatment of central nervous system and cardiovascular diseases PHARMACIA & UPJOHN CO LLC (US) 1997-01-01 CN disclosed
JP-H01242552-A BIPHENYL DERIVATIVE AND PRODUCTION THEREOF SUMITOMO CHEM CO LTD 1989-09-27 JP disclosed
JP-H01242544-A 1-BIPHENYLYLETHANOL DERIVATIVE AND PRODUCTION THEREOF SUMITOMO CHEM CO LTD 1989-09-27 JP disclosed
JP-H01163155-A OPTICALLY ACTIVE 1-BIPHENYLETHANOL DERIVATIVE AND PRODUCTION THEREOF SUMITOMO CHEM CO LTD 1989-06-27 JP disclosed
JP-S6479138-A 1-BIPHENYLYLETHANOL DERIVATIVE AND PRODUCTION THEREOF SUMITOMO CHEMICAL CO 1989-03-24 JP disclosed
EP-0284371-A2 Novel optically active benzene derivatives, process for producing the same and liquid-crystalline substances containing said derivatives as active ingredient and optical switching elements SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-09-28 EP disclosed
EP-0014834-B1 PROCESS FOR THE PREPARATION OF CARBON AMIDES AND OF PEPTIDES HOECHST AKTIENGESELLSCHAFT (DE) 1982-11-03 EP disclosed