Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.64 |
| ▸ | DPP4 | P27487 | 2/20 | 0.56 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.56 |
| ▸ | TLR2 | O60603 | 2/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.54 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.54 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | ACE | P12821 | 1/20 | 0.53 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 3/20 | 0.52 |
| ▸ | ECE1 | P42892 | 1/20 | 0.51 |
| ▸ | CPB1 | P15086 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7765840 | 0.92 | HDAC1 (0.57) | HDAC1HDAC2DPP4DPP8TLR2 | |
| SCHEMBL10886681 | 0.86 | DPP4 (0.55) | HDAC1HDAC2DPP4DPP8SIRT2 | |
| SCHEMBL26477860 | 0.84 | EPHX1 (0.57) | HDAC1HDAC2EPHX1ALDH1A1CTSK | |
| SCHEMBL10706018 | 0.83 | CTSL (0.64) | HDAC1HDAC2EPHX1ALDH1A1CTSK | |
| SCHEMBL7322113 | 0.82 | SIRT2 (0.62) | TLR2SIRT2SIRT1SIRT3CPB2 | |
| SCHEMBL7322118 | 0.82 | SIRT2 (0.62) | TLR2SIRT2SIRT1SIRT3CPB2 | |
| SCHEMBL287475 | 0.81 | ITGB3 (0.66) | DPP4DPP8TLR2SIRT2SIRT1 | |
| SCHEMBL15968143 | 0.81 | ITGB3 (0.66) | DPP4DPP8TLR2SIRT2SIRT1 | |
| SCHEMBL9086439 | 0.81 | ITGB3 (0.60) | HDAC1HDAC2DPP4DPP8TLR2 | |
| SCHEMBL6476819 | 0.81 | ITGB3 (0.66) | DPP4DPP8TLR2SIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230133465-A1 | COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING NEURODEGENERATIVE DISORDERS | ALZHEON, INC. | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230133465-A1 | COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING NEURODEGENERATIVE DISORDERS | PSEN2, CLN6, PSEN1 | HDAC1 1283/4885HDAC2 1230/4885DPP4 870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.