Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CTSK | P43235 | 3/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.53 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 2/20 | 0.53 |
| ▸ | CTSS | P25774 | 1/20 | 0.53 |
| ▸ | TLR2 | O60603 | 2/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.52 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.52 |
| ▸ | DPP4 | P27487 | 2/20 | 0.52 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26477889 | 0.92 | HDAC1 (0.64) | HDAC1HDAC2CTSKALDH1A1TLR2 | |
| SCHEMBL24188458 | 0.83 | ECE1 (0.62) | PRSS1PRSS2PRSS3TPSAB1CTSL | |
| SCHEMBL7317571 | 0.83 | CTSL (0.60) | PRSS1PRSS2PRSS3TPSAB1CTSL | |
| SCHEMBL1841203 | 0.83 | PRSS1 (0.61) | HDAC1HDAC2CTSKPRSS1PRSS2 | |
| SCHEMBL2367228 | 0.83 | ITGB3 (0.64) | PRSS1PRSS2PRSS3TPSAB1CTSL | |
| SCHEMBL210602 | 0.83 | ITGB3 (0.64) | PRSS1PRSS2PRSS3TPSAB1CTSL | |
| SCHEMBL10723335 | 0.83 | PRSS1 (0.61) | HDAC1HDAC2CTSKPRSS1PRSS2 | |
| SCHEMBL1841202 | 0.83 | PRSS1 (0.61) | HDAC1HDAC2CTSKPRSS1PRSS2 | |
| SCHEMBL210601 | 0.83 | ITGB3 (0.64) | PRSS1PRSS2PRSS3TPSAB1CTSL | |
| SCHEMBL7530387 | 0.82 | PRSS1 (0.60) | CTSKPRSS1PRSS2PRSS3TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1101492-A1 | NOVEL REMEDIES FOR ALLERGIC DISEASES | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2001-05-23 | — | — | EP | disclosed |
| EP-1038864-A1 | NOVEL METALLOPROTEINASE INHIBITORS | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2000-09-27 | — | — | EP | disclosed |