Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.62 |
| ▸ | TACR1 | P25103 | 2/20 | 0.60 |
| ▸ | CTSK | P43235 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | CTSS | P25774 | 4/20 | 0.59 |
| ▸ | CTSB | P07858 | 3/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8817011 | 0.94 | EPHX1 (0.58) | CTSLALDH1A1EPHX1TACR1CTSK | |
| SCHEMBL8817014 | 0.94 | EPHX1 (0.58) | CTSLALDH1A1EPHX1TACR1CTSK | |
| SCHEMBL26477860 | 0.86 | EPHX1 (0.57) | CTSLALDH1A1EPHX1CTSKCTSS | |
| SCHEMBL11431644 | 0.84 | ALDH1A1 (0.61) | ALDH1A1EPHX1CTSKHDAC1HDAC2 | |
| Bicarbonate SCHEMBL3824417 | 0.84 | HDAC1 (0.55) | CTSLALDH1A1EPHX1CTSKCTSS | |
| SCHEMBL12856074 | 0.84 | L3MBTL1 (0.60) | CTSLALDH1A1EPHX1KDM4EHDAC1 | |
| SCHEMBL11024260 | 0.84 | TACR1 (0.58) | CTSLTACR1CTSKCTSSCTSB | |
| SCHEMBL26477889 | 0.83 | HDAC1 (0.64) | ALDH1A1EPHX1CTSKHDAC1HDAC2 | |
| SCHEMBL7855475 | 0.83 | ACE (0.54) | CTSLALDH1A1EPHX1CTSKKDM4E | |
| Hydrochloric Acid SCHEMBL7851195 | 0.82 | ACE (0.53) | CTSLALDH1A1EPHX1CTSKKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0135183-B1 | PROCESS FOR THE PREPARATION OF COMPOUNDS CONTAINING CARBOXYLIC ACID AMIDE GROUPS, ESPECIALLY OF PEPTIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-03-30 | — | — | EP | disclosed |
| EP-0135183-A2 | Process for the preparation of compounds containing carboxylic acid amide groups, especially of peptides | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-03-27 | — | — | EP | disclosed |