SCHEMBL26478945

SCHEMBL26478945

O=C(CCc1ccc(Br)cc1)OC1(c2ccccc2)CCNCC1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
PDPK1 O15530 1/20 0.40
MME P08473 1/20 0.40
OPRM1 P35372 4/20 0.40
TDP1 Q9NUW8 2/20 0.39
FFAR1 O14842 2/20 0.39
FFAR4 Q5NUL3 2/20 0.39
POLB P06746 1/20 0.38
CHRM5 P08912 1/20 0.38
CHRM1 P11229 1/20 0.38
CHRM3 P20309 1/20 0.38
DRD3 P35462 1/20 0.37
OPRD1 P41143 3/20 0.36
OPRK1 P41145 3/20 0.36
TACR1 P25103 3/20 0.36
SLC6A4 P31645 1/20 0.36
KCNH2 Q12809 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26479094 0.93 TDP1 (0.45) MEN1KMT2APDPK1MMEOPRM1
SCHEMBL24944317 0.89 OPRM1 (0.40) OPRM1TDP1CHRM5CHRM1CHRM3
SCHEMBL24944681 0.88 OPRM1 (0.40) MEN1KMT2AMMEOPRM1TDP1
SCHEMBL24944045 0.88 OPRM1 (0.45) MEN1KMT2AOPRM1TDP1FFAR1
SCHEMBL26478728 0.88 OPRM1 (0.41) MMEOPRM1OPRD1OPRK1TACR1
SCHEMBL26478943 0.87 L3MBTL1 (0.43) MEN1KMT2AOPRM1TDP1FFAR1
SCHEMBL26479087 0.84 DRD3 (0.46) KMT2AOPRM1POLBDRD3
SCHEMBL26413726 0.84 ALDH1A1 (0.48) MEN1KMT2AKCNH2
SCHEMBL24944056 0.84 HDAC1 (0.44) KMT2AOPRM1TDP1DRD3OPRD1
SCHEMBL26478942 0.83 OPRM1 (0.42) OPRM1FFAR1FFAR4DRD3OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11644753-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-09 US disclosed
US-11644753-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11644753-B2 Resist composition and patterning process HNRNPU, NSUN2, HNRNPR MEN1 3578/4885KMT2A 1033/4885PDPK1 3133/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.