Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.41 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17469801 | 0.83 | LMNA (0.44) | HDAC1HDAC2PRSS1F2PRSS3 | |
| SCHEMBL26485285 | 0.83 | HPGD (0.43) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL7361096 | 0.79 | SMN1; SMN2 (0.41) | HDAC1HDAC2SMN1; SMN2LMNAHTT | |
| SCHEMBL649985 | 0.79 | NAAA (0.54) | HDAC1HDAC2SMN1; SMN2LMNAHTT | |
| SCHEMBL13094265 | 0.78 | MAPT (0.56) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL26485354 | 0.76 | TMPRSS2 (0.54) | HDAC1HDAC2SMN1; SMN2LMNATSHR | |
| SCHEMBL7450887 | 0.76 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNAHTTTSHRL3MBTL1 | |
| SCHEMBL8791205 | 0.75 | SMN1; SMN2 (0.41) | HDAC1HDAC2SMN1; SMN2LMNAHTT | |
| SCHEMBL15846350 | 0.75 | TAS1R3 (0.43) | HDAC1HDAC2SMN1; SMN2LMNAHTT | |
| SCHEMBL12658568 | 0.75 | PRSS1 (0.43) | HDAC1HDAC2PRSS1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183887-A2 | COMPOSITIONS FOR AND METHODS OF MODULATING RNA STABILITY | DUKE UNIVERSITY (US) | 2023-09-28 | — | — | WO | disclosed |