Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 2/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17469801 | 0.82 | LMNA (0.44) | SMN1; SMN2TSHRHTTL3MBTL1HDAC1 | |
| SCHEMBL649985 | 0.81 | NAAA (0.54) | SMN1; SMN2TSHRHTTNAAAHDAC1 | |
| SCHEMBL15846350 | 0.81 | TAS1R3 (0.43) | SMN1; SMN2TSHRHTTL3MBTL1NAAA | |
| SCHEMBL26485348 | 0.79 | HDAC1 (0.43) | SMN1; SMN2TSHRHTTL3MBTL1HDAC1 | |
| SCHEMBL95136 | 0.79 | L3MBTL1 (0.63) | SMN1; SMN2TSHRHTTL3MBTL1NAAA | |
| SCHEMBL7450887 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2TSHRHTTL3MBTL1NAAA | |
| SCHEMBL8791205 | 0.78 | SMN1; SMN2 (0.41) | SMN1; SMN2TSHRHTTL3MBTL1NAAA | |
| Hydrochloric Acid SCHEMBL11725735 | 0.78 | PRSS1 (0.49) | TSHR | |
| SCHEMBL24386523 | 0.77 | HDAC3 (0.47) | L3MBTL1NAAAHDAC1HDAC2HPGD | |
| SCHEMBL13094265 | 0.77 | MAPT (0.56) | TSHRHPGDHDAC3HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091945-A1 | CYCLIC CARBAMATES AND ISOXAZOLIDINES AS IIB/IIIA ANTAGONISTS | Du Pont Pharmaceuticals Company (US) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000000481-A1 | CYCLIC CARBAMATES AND ISOXAZOLIDINES AS IIB/IIIA ANTAGONISTS | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-01-06 | — | — | WO | disclosed |