SCHEMBL264863

SCHEMBL264863

O=Cc1cc(Cl)cc(Br)c1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 13/20 1.00
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
MAPT P10636 2/20 0.41
PIM1 P11309 1/20 0.40
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29852592 1.00 ERN1 (1.00) ERN1MEN1KMT2AMAPTPIM1
SCHEMBL6093685 0.84 ERN1 (1.00) ERN1PIM1ALDH1A1
SCHEMBL2553306 0.81 ERN1 (0.68) ERN1MEN1KMT2AMAPTKDM4E
SCHEMBL2553288 0.81 ERN1 (0.68) ERN1MEN1KMT2AMAPTKDM4E
SCHEMBL456670 0.78 ERN1 (0.78) ERN1PIM1
SCHEMBL29382880 0.78 ERN1 (1.00) ERN1MEN1KMT2AMAPTKDM4E
SCHEMBL29371317 0.78 ERN1 (1.00) ERN1MEN1KMT2AMAPTKDM4E
SCHEMBL30689082 0.78 ERN1 (0.78) ERN1PIM1
SCHEMBL9189245 0.78 ERN1 (0.69) ERN1PIM1
SCHEMBL2120180 0.78 ERN1 (1.00) ERN1MEN1KMT2AMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 255 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117820329-A Spiropyran derivative and synthetic method and application thereof 陕西科技大学 2024-04-05 CN claimed
CN-114113370-B Analysis method of aromatic halogenated disinfection byproducts in water 东南大学 2024-03-26 CN claimed
CN-115677530-B Halogenated Schiff base Zn (II) complex Zn- χ -L and preparation method and application thereof 昆明学院 2023-12-29 CN claimed
CN-117209741-A Preparation method of Schiff base catalyst and preparation method of polyglycolic acid 中国科学院长春应用化学研究所 2023-12-12 CN claimed
CN-115677530-A Halogenated Schiff base Zn (II) complex Zn-chi-L and preparation method and application thereof 昆明学院 2023-02-03 CN claimed
CN-114113370-A Analysis method of aromatic halogenated disinfection byproducts in water 东南大学 2022-03-01 CN claimed
CN-110981772-B Methionine derived Schiff base copper complex and preparation and application thereof 桂林医学院 2020-09-29 CN claimed
CN-110981772-A Methionine derived Schiff base copper complex and preparation and application thereof 桂林医学院 2020-04-10 CN claimed
US-10092786-B2 Fire extinguishing composition comprising aldoketones compound XI'AN WESTPEACE FIRE TECHNOLOGY CO., LTD. (CN) 2018-10-09 US claimed
US-20160332016-A1 Fire Extinguishing Composition Comprising Aldoketones Compound NANO FIRE, LLC 2016-11-17 US claimed
US-20260124309-A1 STAT6 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2026-05-07 US disclosed
US-20260070932-A1 INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF ANNEXON INC (US) 2026-03-12 US disclosed
US-12558341-B2 Oral complement factor D inhibitors BIOCRYST PHARMACEUTICALS, INC. (US) 2026-02-24 US disclosed
US-12509474-B2 Inhibitors of complement factors and uses thereof ANNEXON, INC. (US) 2025-12-30 US disclosed
EP-4665339-A1 INHIBITING ALPHA V BETA 8 INTEGRIN Morphic Therapeutic, Inc. (US) 2025-12-24 EP disclosed
EP-0850221-A1 META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS G.D. SEARLE & CO. (US) 1998-07-01 EP disclosed
US-5710157-A INSECTICIDES FOR AGRICULTURE FMC CORPORATION (US) 1998-01-20 US disclosed
WO-1997008145-A1 META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS G.D. SEARLE & CO. (US) 1997-03-06 WO disclosed
US-5547954-A MIXED WITH AGRICULTURAL ACCEPTABLE CARRIER FMC CORPORATION (US) 1996-08-20 US disclosed
US-5532370-A FOR INSECTS INCLUDING LARVAE SUCH AS TOBACCO BUDWORM FMC CORPORATION (US) 1996-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260124309-A1 STAT6 DEGRADERS AND USES THEREOF STAT6, NCOR2, NCOR1 ERN1 1782/4885MEN1 4497/4885KMT2A 1231/4885
US-12558341-B2 Oral complement factor D inhibitors CFD, CFH, CFB ERN1 3303/4885MEN1 1819/4885KMT2A 4445/4885
US-12509474-B2 Inhibitors of complement factors and uses thereof SSB, UACA, CFH ERN1 912/4885MEN1 2996/4885KMT2A 4351/4885
US-20260070932-A1 INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF CFH, CFB, C5 ERN1 1448/4885MEN1 2993/4885KMT2A 4631/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.