Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2661783 | 0.82 | ALDH1A1 (0.55) | ADRA2CMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL1813872 | 0.80 | MAPT (0.57) | ADRA2CMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL2661540 | 0.78 | ADRA2C (0.54) | ADRA2CMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL2658926 | 0.78 | ADRA2C (0.54) | ADRA2CMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL2659291 | 0.78 | GAA (0.58) | ADRA2CMAPTGFERSMN1; SMN2 | |
| SCHEMBL2661949 | 0.77 | ADRA2C (0.50) | ADRA2CMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL27808023 | 0.77 | ADRA2C (0.60) | ADRA2CMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL2648606 | 0.76 | ADRA2C (0.53) | ADRA2CMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL17976220 | 0.76 | OPRK1 (0.49) | HRH3OPRK1GFER | |
| SCHEMBL17976036 | 0.75 | OPRK1 (0.48) | HRH3ALDH1A1OPRK1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002050057-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES FOR THE TREATMENT OF GABA-ALPHA MEDIATED DISORDERS | NEUROSEARCH A/S (DK) | 2002-06-27 | — | — | WO | disclosed |