Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 3/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.44 |
| ▸ | RAD52 | P43351 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17976220 | 0.99 | OPRK1 (0.49) | OPRK1DRD4OPRD1RAD52SIGMAR1 | |
| SCHEMBL4491465 | 0.88 | DRD4 (0.49) | OPRK1DRD4SIGMAR1ALDH1A1 | |
| SCHEMBL17976248 | 0.86 | DRD4 (0.47) | OPRK1DRD4SIGMAR1POLBHTT | |
| SCHEMBL3148838 | 0.83 | DRD4 (0.48) | OPRK1DRD4RAD52SIGMAR1GFER | |
| SCHEMBL3577293 | 0.83 | DRD4 (0.64) | DRD4HTTALDH1A1HRH3 | |
| SCHEMBL3158672 | 0.81 | DRD4 (0.49) | OPRK1DRD4RAD52SIGMAR1GFER | |
| SCHEMBL30921473 | 0.79 | DRD4 (0.49) | OPRK1DRD4RAD52SIGMAR1GFER | |
| SCHEMBL1937633 | 0.76 | SIGMAR1 (0.43) | SIGMAR1ALDH1A1 | |
| SCHEMBL8355265 | 0.76 | LMNA (0.60) | DRD4SIGMAR1POLBALDH1A1HRH3 | |
| SCHEMBL2648811 | 0.75 | ADRA2C (0.48) | OPRK1GFERALDH1A1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3056202-A1 | BENZOPYRROLIDONE DERIVATIVES POSSESSING ANTIVIRAL AND ANTICANCER PROPERTIES | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2016-08-17 | — | — | EP | disclosed |